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Avacta Group AIM:AVCT

Founded
2004 · Wetherby, England
Incorporated
United Kingdom
Chief executive
Christina Coughlin
Employees
81
Reports in
GBP
Companies House
04748597

Clinical-stage life sciences company developing targeted cancer therapies using its pre|CISION tumour-activated drug delivery platform and Affimer affinity reagents. Lead oncology candidates are in early clinical trials; the group has been divesting diagnostics businesses to focus resources on therapeutics.

Health CareClinical-stage biotechnology
Where the figures come from
How we read

Read straight from the annual reports

Share price and financials

72.0p at close on 2 Oct 2026 · 12 reported years, 2014–2025

Years in viewFY2014 – FY2026
2 Oct 202672.0p−46.5% since 4 Jan 2016
72.0p
LineFY201407/14FY201507/15FY201607/16FY201707/17FY201807/18FY201912/19FY202012/20FY202112/21FY202212/22FY202312/23FY202412/24FY202512/25FY2026unreported
Revenuevs 2.1later 2.9
Gross profitvs 1.2later 2.8
Operating profitvs (18.8)later (23.1)
Adjusted operating profit——————————
Exceptional items———————
Net finance costlater 8.0
Profit before taxvs (18.9)later (31.1)
Tax chargelater (4.7)later (2.0)
Profit for the yearlater (36.6)later (33.3)
EBITDA
Basic EPS
Diluted EPS
Adjusted EPS—————————
Dividend per share————————

GBP millions, negatives in brackets. Per-share lines in pence, share counts in millions. later is what a following report restated the figure to; vs is a second reading that disagrees. The figure shown is the one the original filing printed, and both readings are kept. Click any figure: opens the report page it was read from, highlighted; shows how it was calculated. The share price above is drawn to the same columns: each close sits over the financial year it fell in.

2 figures

12 years, at a glance

GBP · %
010m20m30m-30000%-20000%-10000%0%FY2014FY2025

Dashed: Operating margin, in % on its own scale — read its shape, not its height against the bars.

FY2025Revenue£113kOperating margin−26,454.9%
The latest report

FY2025 annual report

year to 31 Dec 2025 · approved 27 May 2026 · 126 pages · Companies House

Open the reportJSONComing soon
Next report7 May 2027for the year to 31 Dec 2026, the date the register holds, plus this company's usual gap to publication
Sixty seconds on this reportPlaceholder

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From the reportevery line sits on the page it names
What drove revenue

R&D licence/milestone income from AffyXell Therapeutics collaboration (Affimer IP assignment milestones)

Licence-related income of £113,000 in both 2025 and 2024, all attributed to a South Korea-registered customer (AffyXell), 100% of continuing-operations revenue

page 84
And

Divested Diagnostics reagent/test sales (no longer part of the Group)

Discontinued Diagnostics revenue was £6.20 million in 2025 (part-year, to disposal dates) vs £24.31 million in 2024; businesses sold March and August 2025

page 22
What moved the marginheadwind

Increased R&D expenditure as AVA6103 and AVA6000 advance through clinical development

Research costs (continuing operations) rose to £18.76m (2024: £14.27m)

page 23
Andtailwind

Reduction in SG&A following divestment-related headcount and cost reduction

Administrative expenses (continuing) fell to £9.24m (2024: £12.05m), driven by lower personnel costs post executive changes and reduced legal/professional fees

page 23
One-offs in the year

£300k charge: Termination payments and settlement agreements (restructuring)

page 86
What management said

Chairman: 'The coming 9-12 months are crucial for the Company as we anticipate seeing the first evidence of the real potential for our innovative Gen Two pre|CISION platform from our exatecan program, AVA6103.'

page 11
After the year end

27 March 2026: oversubscribed placing and director subscription completed, raising gross proceeds of £10.0 million via 15,000,000 new ordinary shares at 63p plus 873,016 shares under director subscription

page 108
The dividend

No dividend proposed or paid for FY2025 (2024: £nil); Board's stated capital allocation priority is investing in R&D programmes rather than shareholder distributions

page 24
Going concern and the audit

Financial statements prepared on a going concern basis but auditor BDO LLP (senior statutory auditor Shirley Rogan) identified a 'material uncertainty related to going concern' given the Group's dependence on raising further funds (no agreements in place at signing); audit opinion is otherwise unmodified/unqualified. Key Audit Matters for 2025: going concern, valuation of the convertible bond derivative, and accounting for the modification of the convertible bond. Group audit materiality was £0.63m (2% of operating expenses)

page 56
The risks it names first
  • Reliance on third parties (CROs and other partners) supporting clinical and pre-clinical programmesp.27
  • Research and development risk — trials may not succeed or lead to marketable productsp.27
  • Funding risk — cash- and resource-intensive development in a challenging biotech financing/macro environmentp.28
  • Intellectual property risk — ability to obtain/defend patent protection for pre|CISION and Affimerp.28

Read from C000127-AR-2025-ch.

Filings

11 annual reports read, FY2015 to FY2025

Open a year to see what its report said. Every line in it carries the page it was read from.

Sources: Companies House (11)

  1. FY2026Next report expected 7 May 2027

Every figure above,
back to the page it was printed on